Abstract: In February 2023, the European Neuroendocrine Tumor Society (ENETS) offi-cially released guidance paper for digestive neuroendocrine carcinoma. Based on the latest develop-ments and research results, the guidelines provide detailed explanations and practical recommen-dations on the epidemiology, diagnosis, prognostic indicators, treatment, and other aspects of digestive neuroendocrine carcinoma. The authors aim to interpret the key contents of the guidelines in order to further provide standardized clinical diagnosis and treatment processes.