Abstract: Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in China. Most HCC patients complicate with chronic liver disease and/or cirrhosis, and need being provided overall consideration and whole‑course management on diagnosis, treatment and follow-up. To develop a reasonable, long‑term, and complete management plan, multiple factors need to be considered, including patient′s general condition, basic liver diseases, tumor stage, tumor biological characteristics, treatment requirements and economic cost. To better guide the whole‑course manage-ment of HCC patients, the Chinese Association of Liver Cancer of Chinese Medical Doctor Associa-tion has gathered multidisciplinary experts and scholars in relevant fields to formulate the Chinese Expert Consensus on the Whole‑course Management of Hepatocellular Carcinoma (2023 Edition). Based on the current clinical evidences and experiences, this expert consensus proposes surgical and non‑surgical HCC management pathways,contains 18 recommendations, including perioperative treatment, systematic treatment or combined with local treatment, conversion treatment, special population management, symptomatic support treatment, and follow‑up management, etc, in order to provide references to domestic collegues.