Abstract: Pancreatic diseases is a kind of complex, high‑risk gastrointestinal diseases. Pancreatic cancer is highly malignant and seriously endangers people′s health. Developing multi-center, large‑scale real world research can better understand the incidence patterns and treatment outcomes of pancreatic diseases. Based on the multi‑center and heterogeneous data, the authors for-mulate data standards for real world studies of pancreatic diseases, and build a database of pancreatic cancer, integrating and sharing data from multi‑center sources, in order to fully explore the scientific research value of pancreatic cancer clinical information, and provide experience and reference for the construction of other real world research specific disease databases in the future.