Abstract: Organ transplantation is the most effective treatment for end stage organ failure, and voluntary donation after citizen's death is the only source of transplanted organ in China. Clinically, transplantation organ protection technology plays a critical role in improving the quality of transplantation organs and the prognosis of recipients. On the basis of domestic and worldwide basic research and clinical practice and according to the Oxford evidence classification and GRADE system, the experts organized by Organ Transplantation Doctor Branch of Chinese Medical Doctor Association, Organ Transplantation Group in Surgery Branch of Chinese Medical Association and China Liver Transplant Registry Scientific Committee had compiled and published theChinese Expert Consensus on Organ Protection of Transplantation (2016 edition) (hereinafter referred to as the 2016 edition consensus) for liver, kidney, pancreas, small intestine, heart, lung transplantation organs. With the support of China Liver Transplant Registry, National Center for Healthcare Quality Management in Liver Transplant, National Quality Control Center for Donated Organ Procurement, National Clinical Research Center for Orthopedics, Sports Medicine & Rehabilitation and National Trauma Medical Organ Protection Committee and combined with recent domestic and worldwide clinical practice and research progress for organ transplantation and organ protection, theChinese Expert Consensus on Organ Protection of Transplantation (2022 edition) (hereinafter referred to as the consensus) has been formulated in 2022. This edition of the consensus focuses on updating the technical progress and evidence-based medicine of organ procurement, organ preservation, organ transport, and quality evaluation in clinical practice. Additionally, protection of composite tissue for transplantation, mainly including limb graft, has also been included. The organ protection strategy recommended in this consensus aims to promote scientific and standardized clinical organ transplantation work.