Abstract: Although China is a big country of hepatobiliary diseases, the development of big data in hepatobiliary diseases lags behind. At present, there is no national standard for hepatobiliary clinical and imaging data, and there is no expert consensus on standardized labeling of hepatobiliary diseases in the industry. To solve this problem, the National Health Commission organize the national hepatobiliary experts to formulate the 'standard data specification for liver and gallbladder diseases'. In this paper, the authors analyze the background, main contents and clinical significance of the 'standard data specification for liver and gallbladder diseases', including standards with standard No. T/CMDA 001-2020, T/CMDA 002-2020 and T/CMDA 003-2020, in order to promote the understanding of standards of data acquisition, labeling and quality control in clinical medical research and artificial intelligence medical device, and to facilitate the popularization and application of this standard.