Abstract: Postoperative anastomosis-related complications are the common postoperative complications of gastric cancer. With the advancement of surgical technology and surgical instruments, the risk of postoperative anastomosis-related complications of gastric cancer has been greatly reduced. However, anastomotic stenosis, residual gastritis, anastomosis inflammation and reflux esophagitis seriously affect long-term quality of life in gastric cancer patients. Based on the incidence of short-term and long-term complications, the authors aim to conclude risks factors, preventive measures and means of treatment for postoperative anastomosis-related complications after gastric cancer surgery.