Abstract: The incidence of adenocarcinoma of esophagogastric junction (AEG) is increasing year by year. Surgical treatment is the most important treatment in the multidisciplinary comprehensive treatment. Because of the particularity of anatomy and biological behaliars, there are many disputes in surgical treatment. It mainly focuses on the choice of surgical approach, scope of surgical resection and guarantee of the safety of surgical margin, scope of lymph node dissection, choice of digestive tract reconstruction after radical operation, role of neoadjuvant treatment in surgical treatment, etc, which need to be confirmed through more randomized clinical studies. The authors discuss the disputes of the surgical diagnosis and treatment strategies of Siewert Ⅱ AEG in the era of minimally invasive surgery.